Lack of inhibitory interaction between somatosensory afferent inputs and intracortical inhibitory interneurons in focal hand dystonia
Identifieur interne : 000361 ( France/Analysis ); précédent : 000360; suivant : 000362Lack of inhibitory interaction between somatosensory afferent inputs and intracortical inhibitory interneurons in focal hand dystonia
Auteurs : Marion Simonetta-Moreau [France] ; George Lourenço [France] ; Sophie Sangla [France] ; Leonor Mazieres [France] ; Marie Vidailhet [France] ; Sabine Meunier [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-06-06.
English descriptors
- KwdEn :
- Adolescent, Adult, Afferent Pathways (physiopathology), Dystonic Disorders (physiopathology), Dystonic Disorders (therapy), Female, Fingers (innervation), Hand (innervation), Humans, Interneurons (physiology), Male, Middle Aged, Motor Activity, Reference Values, Somatosensory Cortex (physiopathology), Transcranial Magnetic Stimulation, Treatment Outcome, cutaneous afferents, focal hand dystonia, muscle afferent input, sensorimotor system, transcranial magnetic stimulation.
- MESH :
- innervation : Fingers, Hand.
- physiology : Interneurons.
- physiopathology : Afferent Pathways, Dystonic Disorders, Somatosensory Cortex.
- therapy : Dystonic Disorders.
- Adolescent, Adult, Female, Humans, Male, Middle Aged, Motor Activity, Reference Values, Transcranial Magnetic Stimulation, Treatment Outcome.
Abstract
We looked for an impaired interaction in the primary motor cortex between intracortical inhibitory circuits and circuits fed by somatosensory inputs in patients with writer's cramp. Short‐interval intracortical inhibition (sICI) to wrist extensor carpi radialis muscle (ECR) was conditioned by stimulation of antagonist muscle afferents and sICI to first dorsal interosseus (FDI) muscle by homotopic cutaneous afferents stimulation. sICI was assessed at rest and during a tonic contraction of the target muscle. Eighteen patients with writer's cramp (10 having a wrist dystonic posture in flexion during writing and 8 in extension) were compared to 14 control subjects. Peripheral inputs decreased sICI in control subjects. This decrease was lost in patients in both FDI and ECR, regardless of the wrist dystonic posture. By contrast, contraction‐induced depression of sICI appeared dependant on the dystonic status of the muscle: depression of sICI to ECR was abolished in patients with wrist dystonic posture in flexion, but not in patients with dystonic posture in extension, sICI even giving way to motor‐evoked potential facilitation. Loss of interaction between interneurons mediating sICI and peripheral inputs probably belongs to the initial abnormalities underlying dystonia. Lack of peripherally induced sICI modulation may oppose wrist and/or hand muscles synergies. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.20821
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000554
- to stream Istex, to step Curation: 000554
- to stream Istex, to step Checkpoint: 001E24
- to stream PubMed, to step Corpus: 002D44
- to stream PubMed, to step Curation: 002D44
- to stream PubMed, to step Checkpoint: 002C56
- to stream Ncbi, to step Merge: 001587
- to stream Ncbi, to step Curation: 001587
- to stream Ncbi, to step Checkpoint: 001587
- to stream Main, to step Merge: 004678
- to stream Main, to step Curation: 003365
- to stream Main, to step Exploration: 003365
- to stream France, to step Extraction: 000361
Links to Exploration step
ISTEX:52DCCC31175ADC6E5FDC69E231B322C54B5F7C84Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lack of inhibitory interaction between somatosensory afferent inputs and intracortical inhibitory interneurons in focal hand dystonia</title><author><name sortKey="Simonetta Oreau, Marion" sort="Simonetta Oreau, Marion" uniqKey="Simonetta Oreau M" first="Marion" last="Simonetta-Moreau">Marion Simonetta-Moreau</name></author><author><name sortKey="Lourenco, George" sort="Lourenco, George" uniqKey="Lourenco G" first="George" last="Lourenço">George Lourenço</name></author><author><name sortKey="Sangla, Sophie" sort="Sangla, Sophie" uniqKey="Sangla S" first="Sophie" last="Sangla">Sophie Sangla</name></author><author><name sortKey="Mazieres, Leonor" sort="Mazieres, Leonor" uniqKey="Mazieres L" first="Leonor" last="Mazieres">Leonor Mazieres</name></author><author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name></author><author><name sortKey="Meunier, Sabine" sort="Meunier, Sabine" uniqKey="Meunier S" first="Sabine" last="Meunier">Sabine Meunier</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:52DCCC31175ADC6E5FDC69E231B322C54B5F7C84</idno><date when="2006" year="2006">2006</date><idno type="doi">10.1002/mds.20821</idno><idno type="url">https://api.istex.fr/document/52DCCC31175ADC6E5FDC69E231B322C54B5F7C84/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000554</idno><idno type="wicri:Area/Istex/Curation">000554</idno><idno type="wicri:Area/Istex/Checkpoint">001E24</idno><idno type="wicri:doubleKey">0885-3185:2006:Simonetta Oreau M:lack:of:inhibitory</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:16532446</idno><idno type="wicri:Area/PubMed/Corpus">002D44</idno><idno type="wicri:Area/PubMed/Curation">002D44</idno><idno type="wicri:Area/PubMed/Checkpoint">002C56</idno><idno type="wicri:Area/Ncbi/Merge">001587</idno><idno type="wicri:Area/Ncbi/Curation">001587</idno><idno type="wicri:Area/Ncbi/Checkpoint">001587</idno><idno type="wicri:doubleKey">0885-3185:2006:Simonetta Moreau M:lack:of:inhibitory</idno><idno type="wicri:Area/Main/Merge">004678</idno><idno type="wicri:Area/Main/Curation">003365</idno><idno type="wicri:Area/Main/Exploration">003365</idno><idno type="wicri:Area/France/Extraction">000361</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Lack of inhibitory interaction between somatosensory afferent inputs and intracortical inhibitory interneurons in focal hand dystonia</title><author><name sortKey="Simonetta Oreau, Marion" sort="Simonetta Oreau, Marion" uniqKey="Simonetta Oreau M" first="Marion" last="Simonetta-Moreau">Marion Simonetta-Moreau</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>U455 INSERM, Fédération de Neurologie, CHU Purpan, Toulouse</wicri:regionArea><placeName><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Lourenco, George" sort="Lourenco, George" uniqKey="Lourenco G" first="George" last="Lourenço">George Lourenço</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>U731 INSERM/UPMC, Médecine Physique et Réadaptation (Pr. Perrigot), Hôpital de la Salpêtrière, Paris</wicri:regionArea><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Sangla, Sophie" sort="Sangla, Sophie" uniqKey="Sangla S" first="Sophie" last="Sangla">Sophie Sangla</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU St. Antoine, Paris</wicri:regionArea><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mazieres, Leonor" sort="Mazieres, Leonor" uniqKey="Mazieres L" first="Leonor" last="Mazieres">Leonor Mazieres</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>U731 INSERM/UPMC, Médecine Physique et Réadaptation (Pr. Perrigot), Hôpital de la Salpêtrière, Paris</wicri:regionArea><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU St. Antoine, Paris</wicri:regionArea><placeName><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>U289 INSERM, Hôpital de la Salpêtrière, Paris</wicri:regionArea><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Meunier, Sabine" sort="Meunier, Sabine" uniqKey="Meunier S" first="Sabine" last="Meunier">Sabine Meunier</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>U731 INSERM/UPMC, Médecine Physique et Réadaptation (Pr. Perrigot), Hôpital de la Salpêtrière, Paris</wicri:regionArea><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-06-06">2006-06-06</date><biblScope unit="vol">21</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="824">824</biblScope><biblScope unit="page" to="834">834</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">52DCCC31175ADC6E5FDC69E231B322C54B5F7C84</idno><idno type="DOI">10.1002/mds.20821</idno><idno type="ArticleID">MDS20821</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Afferent Pathways (physiopathology)</term><term>Dystonic Disorders (physiopathology)</term><term>Dystonic Disorders (therapy)</term><term>Female</term><term>Fingers (innervation)</term><term>Hand (innervation)</term><term>Humans</term><term>Interneurons (physiology)</term><term>Male</term><term>Middle Aged</term><term>Motor Activity</term><term>Reference Values</term><term>Somatosensory Cortex (physiopathology)</term><term>Transcranial Magnetic Stimulation</term><term>Treatment Outcome</term><term>cutaneous afferents</term><term>focal hand dystonia</term><term>muscle afferent input</term><term>sensorimotor system</term><term>transcranial magnetic stimulation</term></keywords><keywords scheme="MESH" qualifier="innervation" xml:lang="en"><term>Fingers</term><term>Hand</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Interneurons</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Afferent Pathways</term><term>Dystonic Disorders</term><term>Somatosensory Cortex</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dystonic Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Motor Activity</term><term>Reference Values</term><term>Transcranial Magnetic Stimulation</term><term>Treatment Outcome</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We looked for an impaired interaction in the primary motor cortex between intracortical inhibitory circuits and circuits fed by somatosensory inputs in patients with writer's cramp. Short‐interval intracortical inhibition (sICI) to wrist extensor carpi radialis muscle (ECR) was conditioned by stimulation of antagonist muscle afferents and sICI to first dorsal interosseus (FDI) muscle by homotopic cutaneous afferents stimulation. sICI was assessed at rest and during a tonic contraction of the target muscle. Eighteen patients with writer's cramp (10 having a wrist dystonic posture in flexion during writing and 8 in extension) were compared to 14 control subjects. Peripheral inputs decreased sICI in control subjects. This decrease was lost in patients in both FDI and ECR, regardless of the wrist dystonic posture. By contrast, contraction‐induced depression of sICI appeared dependant on the dystonic status of the muscle: depression of sICI to ECR was abolished in patients with wrist dystonic posture in flexion, but not in patients with dystonic posture in extension, sICI even giving way to motor‐evoked potential facilitation. Loss of interaction between interneurons mediating sICI and peripheral inputs probably belongs to the initial abnormalities underlying dystonia. Lack of peripherally induced sICI modulation may oppose wrist and/or hand muscles synergies. © 2006 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>France</li></country><settlement><li>Paris</li><li>Toulouse</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Simonetta Oreau, Marion" sort="Simonetta Oreau, Marion" uniqKey="Simonetta Oreau M" first="Marion" last="Simonetta-Moreau">Marion Simonetta-Moreau</name></noRegion><name sortKey="Lourenco, George" sort="Lourenco, George" uniqKey="Lourenco G" first="George" last="Lourenço">George Lourenço</name><name sortKey="Mazieres, Leonor" sort="Mazieres, Leonor" uniqKey="Mazieres L" first="Leonor" last="Mazieres">Leonor Mazieres</name><name sortKey="Meunier, Sabine" sort="Meunier, Sabine" uniqKey="Meunier S" first="Sabine" last="Meunier">Sabine Meunier</name><name sortKey="Sangla, Sophie" sort="Sangla, Sophie" uniqKey="Sangla S" first="Sophie" last="Sangla">Sophie Sangla</name><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000361 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000361 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= France
|étape= Analysis
|type= RBID
|clé= ISTEX:52DCCC31175ADC6E5FDC69E231B322C54B5F7C84
|texte= Lack of inhibitory interaction between somatosensory afferent inputs and intracortical inhibitory interneurons in focal hand dystonia
}}
| This area was generated with Dilib version V0.6.23. |  |